(sar-GRAM-oh-stim)
NEWLY DISCOVERED USES (OFF-LABEL)
Aplastic anemia, agranulocytosis, HIV
ORIGINAL USES (ON-LABEL)
Recovery of blood factors after bone marrow transplantation, peripheral stem cell transplantation.
BRAND NAME
Leukine
DRUG CLASS
Colony-stimulating factor (blood factor)
DESCRIPTION
This drug stimulates the production of several important factors in the blood for promoting immune response against the growth of cancer cells or recovery of cells after chemotherapy.
POTENTIAL SIDE EFFECTS
Increased or decreased blood pressure, bleeding, increased heart rate, headache, numbness, insomnia, anxiety, rash, hair loss, itching, nausea, diarrhea, vomiting, abdominal pain,
mouth ulcers, stomach upset, anorexia, difficulty swallowing, constipation, increased bilirubin, changes in blood, bone pain, muscle aches, sore throat, shortness of breath, fever, infection, weight loss.
CAUTIONS
- This product is produced from yeast derived products and thus should not be used by persons allergic to yeasts.
- Notify your doctor if you have cardiac problems, fluid retention, lung disorders, liver or kidney impairment. Notify your doctor is you are receiving chemotherapy or radiation.
- Contains benzyl alcohol.
- May cause rapid increase in platelets.
DRUG INTERACTIONS
Lithium, corticosteroids
FOOD INTERACTIONS
Unknown
HERBAL INTERACTIONS
Unknown
PREGNANCY AND BREAST-FEEDING CAUTIONS
Category C. Excretion in breast milk is unknown. Consult your doctor.
SPECIAL INFORMATION
Requires extensive laboratory monitoring.
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